Support PLUS & Resources

Support PLUS Provides Information and Support for Reimbursement

  • Patient benefit investigation
  • Predetermination, prior authorization, and appeal support
  • Specialty pharmacy triage and follow-up
  • Outbound welcome calls and nurse follow-up
  • Live nurse support


Support PLUS representatives are available from 7 AM–7 PM CST Monday through Friday at  
1-855-LUPRON-P (1-855-587-7667) to help with any questions you may have.


With the Instant Savings Card, Eligible Patients* Pay as Little as $10 per Prescription of Lupron Depot-Ped

Instant Savings Card


Eligible patients* pay as little as $10 per prescription of

With the Instant Savings Card, your patients can save up to $250 (up to $3,000/year) on 1-month dosing and up to $1,000 (up to $4,000/year) on 3-month dosing for each prescription after a $10 co-pay expense.

Pharmacy Benefit: Your patients can use their Instant Savings Card at the pharmacy at the time of purchase and have it applied to their co-pay and/or deductible.

Medical Benefit: If the pharmacist is not available to provide instant savings, your patients can take advantage of the Instant Savings Card by:


Starting and
activating the card


Mailing in
the rebate

*Eligibility: Available to patients with commercial prescription insurance coverage for LUPRON DEPOT-PED who meet eligibility criteria. Co-pay assistance program is not available to patients receiving prescription reimbursement under any federal, state or government-funded insurance programs (for example, Medicare (including Part D), Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If at any time the patient begins receiving prescription drug coverage under any such federal, state or government-funded healthcare program, patient will no longer be able to use the LUPRON DEPOT-PED Instant Savings Card and patient must call 1-877-832-9755 to stop participation. Patients residing in or receiving treatment in certain states may not be eligible. Patients may not seek reimbursement for value received from the Instant Savings Card from any third-party payers. Offer subject to change or discontinuance without notice. Restrictions, including monthly maximums, may apply. This is not health insurance.


Nurse Support Hotline

Parents and caregivers of children on LUPRON DEPOT-PED can speak to a certified registered nurse about diagnosis, treatment, co-pay issues, and more, at no cost.

Toll-free hotline: 1-855-LUPRON-P (1-855-587-7667), Monday–Saturday, 7 AM–7 PM CST

The CPP Tracker is a smartphone app, which is available at no additional cost, that helps parents and caregivers manage their child’s journey during treatment for CPP.

The CPP Tracker makes it simple for parents and caregivers to keep up to date with their physician appointments and track their child’s progress anywhere they go.

The CPP Tracker includes the following features:

alttextAppointment calendar link and reminders

alttextWhat to expect from treatment

alttextQuestions for the physician

alttextNurse hotline direct call

alttextInstant savings card information

Your CPP caregivers and patients have access to a brochure designed especially for them: Facing Central Precocious Puberty: A step-by-step plan for your CPP journey.

The brochure discusses the following topics:

  • What is CPP?
  • Possible complications of CPP
  • Why the physician chose treatment with LUPRON DEPOT-PED
  • What to expect during treatment
  • Support PLUS assistance


Medical Necessity Letter

The guidance presented here is for informational purposes only and is not intended to provide reimbursement or legal advice. AbbVie does not guarantee that the use of any information provided will result in coverage or payment by any third-party payer. You are responsible for the submission based on your clinical judgment.

Medical Necessity Letter

Download the sample Medical Necessity Letter

Medical Necessity Letter